Drotaverine HCl and Mefenamic Acid
Brand Name: Ziadrene
Composition: Drotaverine Hcl 80 mg + Mefenamic Acid 250 mg
MRP: 1150
Packing: 10×10 Alu/Alu
Table of Contents
Key Highlights
Ziadrene combines drotaverine hydrochloride and mefenamic acid tablet for powerful relief from cramps, spasms, and abdominal pain.
Highly effective in menstrual cramps (dysmenorrhea), gastrointestinal spasms, and renal/biliary colic.
Drotaverine relaxes smooth muscles; mefenamic acid reduces pain & inflammation.
Fast onset of action and long-lasting relief.
WHO-GMP certified manufacturing by Biozia Lifesciences.
Product Overview
Ziadrene is a scientifically formulated drotaverine hydrochloride and mefenamic acid tablet designed for fast, targeted relief from spasmodic pain. This combination is especially effective in treating menstrual cramps, stomach cramps, intestinal spasms, gallbladder pain, and urinary tract spasms.
Drotaverine is a trusted antispasmodic widely prescribed for smooth muscle relaxation, while mefenamic acid is an NSAID that reduces inflammation and pain. Together, they provide immediate and long-lasting comfort.
For distributors and PCD partners, Ziadrene is a high-volume product due to strong demand in gynecology, general medicine, and gastro specialties.
Indications for Drotaverine Hydrochloride and Mefenamic Acid Tablet
The drotaverine hydrochloride and mefenamic acid tablet is indicated for:
Menstrual pain (dysmenorrhea)
Abdominal cramps
Irritable bowel syndrome (IBS)-related spasms
Gastrointestinal colic
Renal colic / ureteric spasms
Biliary colic (gallbladder-related pain)
Postoperative spasmodic pain
Pain due to smooth muscle contractions in uterus, stomach, or intestines
Doctors often prefer this combination for rapid and reliable relief from deep-seated muscle spasms.
Mechanism of Action
Drotaverine Hydrochloride
A selective phosphodiesterase-4 inhibitor, which increases smooth muscle relaxation and reduces spasms.
Mefenamic Acid
A non-steroidal anti-inflammatory drug (NSAID) that blocks prostaglandin synthesis.
Reduces inflammation, pain, and tissue irritation.
Together, the drotaverine hydrochloride and mefenamic acid tablet provides relief by relaxing spasming muscles and controlling inflammation.
Dosage and Administration for Ziadrene
Standard adult dosage: 1 tablet 2–3 times a day, or as prescribed.
Best taken after food to reduce stomach discomfort.
Swallow whole with water; do not crush unless directed.
Avoid alcohol as it increases gastric irritation.
Not recommended for patients with severe kidney/liver issues unless supervised.
Pregnant women should take this only under medical guidance
General Health & Recovery Tips
Apply warm compress to relieve uterine or abdominal spasms.
Hydrate well — dehydration increases muscle spasm intensity.
Avoid heavy oily meals that worsen gastric discomfort.
For menstrual cramps, light walking or stretching helps.
Maintain regular sleep patterns — pain worsens with fatigue.
Do not mix multiple painkillers with Ziadrene unless prescribed.
Myths & Facts About Drug Levocetirizine
Myth: “This combination works only for menstrual pain.”
Fact: It works for any smooth muscle spasm, including GI, urinary and biliary spasms.
Myth: “Stronger pain means doubling the dose.”
Fact: Overdosing increases risks (gastric upset, kidney load) without improving relief.
Myth: “Drotaverine causes sedation.”
Fact: Drotaverine is non-sedating and does not impair alertness.
Myth: “Mefenamic acid is unsafe.”
Fact: Safe when used correctly and for short durations as prescribed.
Myth: “You only need it when pain peaks.”
Fact: Consistency (as per doctor’s advice) leads to better control of spasms.
Did You Know?
Drotaverine works on smooth muscles without affecting the nervous system — making it ideal for stomach and period cramps.
Mefenamic acid is one of the most commonly used NSAIDs for menstrual pain globally.
The combination often reduces the need for injectable pain medicines in spasmodic conditions.
Once pain is controlled early, spasms reduce significantly in subsequent episodes.
Why Choose Biozia Lifesciences?
At Biozia Lifesciences Pvt. Ltd., we believe that quality healthcare should be affordable and accessible. Our products are:
Manufactured in WHO-GMP certified units.
Backed by strong quality testing at every stage.
Packed securely to maintain potency and shelf life.
Trusted by healthcare professionals across India.
We are more than just a pharmaceutical company — we are partners in improving community health.
Why Partner With Us?
Monopoly-based franchise rights.
Wide product range across antibiotics, nutraceuticals, pain relief, syrups, and more.
Attractive packaging and marketing materials (visual aids, brochures, samples).
Timely delivery and stock availability.
Dedicated business support to help you grow your pharma business.
👉 Contact us today to explore franchise opportunities in your region.
This information is provided for educational purposes only and does not substitute medical advice. Always consult a qualified physician or pharmacist before starting any medication. The use of this product must comply with local regulations. Biozia Lifesciences is not liable for misuse
FAQ
Q1. What are drotaverine hydrochloride and mefenamic acid tablets used for?
They are used for abdominal cramps, menstrual pain, urinary spasms, GI spasms, and biliary/renal colic.
Q2. How fast does Ziadrene work?
Most patients feel relief within 30–45 minutes
Q3. Can I take Ziadrene on an empty stomach?
Not recommended — it may increase gastric discomfort
Q4. Is it safe during periods?
Yes, it is widely prescribed for menstrual cramps
Q5. Can it be taken with other painkillers?
Avoid combining with NSAIDs unless prescribed to prevent stomach irritation