Doxofylline 400mg
Brand Name: Ziafyl-400
Composition: Doxofylline 400mg
MRP: 800
Packing: 10×10 Blister
Table of Contents
Product Overview
Ziafyl-400 contains Doxofylline 400mg, a modern xanthine derivative widely used in the treatment of asthma, COPD (Chronic Obstructive Pulmonary Disease), and bronchospasm. Unlike traditional theophylline, it offers better safety, fewer side effects, and improved tolerability, making it a preferred prescription for respiratory conditions.
Manufactured under ISO and WHO-GMP certification by Biozia Lifesciences, Ziafyl-400 is trusted by doctors for its effectiveness and by franchise partners for its high demand in respiratory medicine.
Indications for Doxofylline 400mg
Ziafyl-400 is prescribed in multiple respiratory disorders where airway obstruction or bronchospasm is a concern:
Asthma – Helps prevent and control chronic symptoms like breathlessness, wheezing, and chest tightness (PubMed)
Chronic Obstructive Pulmonary Disease (COPD) – Improves airflow and reduces exacerbations in long-term smokers and COPD patients (NCBI)
Chronic Bronchitis – Reduces airway inflammation and mucus buildup
Emphysema – Helps patients with damaged air sacs in the lungs breathe more easily
Exercise-Induced Bronchospasm – Prevents sudden airway narrowing during or after physical activity
Allergic Airway Disorders – Provides symptomatic relief in bronchospasms triggered by allergens
Post-Respiratory Infections – Used in managing prolonged cough and wheezing following infections
Combination Therapy – Sometimes prescribed with inhalers and steroids for better respiratory control
Mechanism of Action
Doxofylline is a xanthine derivative with a unique pharmacological profile:
Bronchodilation: Relaxes smooth muscles of the airway, improving airflow
Phosphodiesterase Inhibition: Increases cyclic AMP (cAMP) levels, leading to relaxation of bronchial muscles
Anti-Inflammatory Effect: Reduces airway inflammation and hyperresponsiveness
Safer Profile: Unlike theophylline, Doxofylline has minimal cardiovascular and neurological side effects, making it safer for long-term use (ScienceDirect)
Dosage and Administration for Ziafyl-400
Adults: Typically 400 mg once or twice daily, or as directed by a physician
Best taken after meals to reduce stomach irritation
Do not crush or chew; swallow whole with water
Dosage may vary depending on patient’s condition and response
General Health & Recovery Tips
Avoid smoking and exposure to air pollutants
Perform breathing exercises like pranayama and pursed-lip breathing
Maintain a healthy diet with antioxidants (fruits, vegetables) to reduce lung inflammation
Stay hydrated to thin mucus in airways
Take regular vaccinations (flu, pneumonia) to prevent complications
Monitor peak expiratory flow rate (PEFR) if advised by your doctor
Myths & Facts About Doxofylline
Myth: Asthma can be completely cured with medicines.
Fact: Asthma is a chronic condition; medicines like Doxofylline help manage symptoms effectively.
Myth: COPD only affects smokers.
Fact: While smoking is a major cause, COPD can also affect non-smokers exposed to pollution or occupational hazards.
Myth: Doxofylline is the same as theophylline.
Fact: Doxofylline is a safer alternative with fewer cardiac and CNS side effects.
Did You Know?
COPD is the third leading cause of death worldwide (WHO)
Asthma affects over 300 million people globally, with rising prevalence in urban India
Doxofylline is considered a “new generation xanthine” due to its safety profile
Respiratory medicines like Ziafyl-400 are in high demand in PCD Pharma Franchise networks
Regular therapy can significantly improve quality of life in patients with chronic respiratory illness
Why Choose Biozia Lifesciences?
At Biozia Lifesciences Pvt. Ltd., we believe that quality healthcare should be affordable and accessible. Our products are:
Manufactured in WHO-GMP certified units.
Backed by strong quality testing at every stage.
Packed securely to maintain potency and shelf life.
Trusted by healthcare professionals across India.
We are more than just a pharmaceutical company — we are partners in improving community health.
Why Partner With Us?
Monopoly-based franchise rights.
Wide product range across antibiotics, nutraceuticals, pain relief, syrups, and more.
Attractive packaging and marketing materials (visual aids, brochures, samples).
Timely delivery and stock availability.
Dedicated business support to help you grow your pharma business.
👉 Contact us today to explore franchise opportunities in your region.
This information is provided for educational purposes only and does not substitute medical advice. Always consult a qualified physician or pharmacist before starting any medication. The use of this product must comply with local regulations. Biozia Lifesciences is not liable for misuse
FAQ
Q1. What is Ziafyl-400 used for?
It is used for treating asthma, COPD, chronic bronchitis, and other airway obstruction conditions.
Q2. Is Ziafyl-400 safer than theophylline?
Yes, Doxofylline has a better safety profile, with fewer heart and neurological side effects.
Q3. Can it be taken with inhalers or steroids?
Yes, it is often prescribed as part of combination therapy. Always follow doctor’s advice.
Q4. Are there side effects?
Mild nausea, headache, or stomach discomfort may occur. Serious side effects are rare.
Q5. Can it be used in elderly patients?
Yes, it is generally safe, but dosage should be monitored by a physician.
Q6. Is Ziafyl-400 available for PCD Pharma Franchise distribution?
Yes, Biozia Lifesciences provides Ziafyl-400 as part of its respiratory care portfolio.