Aceclofenac, Paracetamol & Chlorzoxazone Tablets: Uses & Dosage

Reviewed by Anil Kumar Goel, B.Pharm — Chairman, Biozia Lifesciences, 40+ years in the pharmaceutical industry.

The combination of aceclofenac, paracetamol and chlorzoxazone is one of the most widely prescribed treatments for painful muscle spasm — back pain, sprains and strains. It pairs an anti-inflammatory, a pain reliever and a muscle relaxant in one tablet. Here is how the combination works, how it is used, what to watch for, and how Biozia supplies it as Zianac-Forte Tablet.

Key takeaways (TL;DR)

Each tablet combines Aceclofenac 100 mg (NSAID), Paracetamol 325 mg (analgesic) and Chlorzoxazone 250 mg (centrally acting muscle relaxant).
Used for musculoskeletal pain with muscle spasm: low back pain, neck pain, sprains, strains and post-injury stiffness.
Usually taken one tablet twice daily after food, for a short course as prescribed.
Can cause drowsiness; alcohol and driving should be avoided.
Biozia supplies it as Zianac-Forte (10×10 blister) for PCD franchise and third-party manufacturing.

Composition and available strengths

Biozia manufactures this fixed-dose combination as:

Brand	Composition	Packing
Zianac-Forte Tablet	Aceclofenac 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg	10×10 Blister

How the combination works

Each ingredient targets a different part of the problem. Aceclofenac blocks prostaglandin production to reduce inflammation and swelling. Paracetamol adds central pain relief and lowers fever. Chlorzoxazone acts on the spinal cord and brain to relieve muscle spasm, which breaks the cycle of pain causing spasm and spasm causing more pain.

Uses

Acute low back pain and neck pain with muscle spasm
Sprains, strains and sports injuries
Painful muscle spasm after trauma or overexertion
Musculoskeletal pain associated with arthritis flare-ups, as prescribed

Dosage and how to take

The usual adult dose is one tablet twice daily after meals, swallowed whole with water. Treatment is normally short-term. Total daily paracetamol from all sources should not exceed the recommended limit, so patients should not take other paracetamol-containing products at the same time.

Side effects

Possible side effects include nausea, indigestion, abdominal pain, drowsiness, dizziness and headache. Chlorzoxazone can occasionally colour the urine orange or reddish-purple, which is harmless. Rarely, chlorzoxazone and paracetamol can affect the liver — yellowing of the eyes or skin, dark urine or persistent stomach pain need prompt medical attention.

Precautions and contraindications

Avoid in active peptic ulcer, gastrointestinal bleeding, or known allergy to NSAIDs or any ingredient.
Use with caution in liver disease, kidney disease, heart disease or high blood pressure.
Avoid alcohol; it increases drowsiness and liver risk.
Do not drive or operate machinery if drowsy.
Not recommended in pregnancy (especially the third trimester), breastfeeding or children unless advised by a doctor.

For distributors: PCD franchise and third-party manufacturing

Muscle-relaxant combinations are a high-volume prescription category for orthopaedic surgeons, physiotherapy clinics and general physicians. Zianac-Forte sits naturally beside Biozia’s other pain products, such as Zianac-P (aceclofenac + paracetamol) and Dicrex-MR (diclofenac + chlorzoxazone + paracetamol).

PCD franchise — stock Zianac-Forte under monopoly rights in your district. See PCD pharma franchise with Biozia.
Third-party manufacturing — get this formulation made under your own brand name. See third-party manufacturing services.
Quality — WHO-GMP and ISO certified manufacturing in Yamunanagar, Haryana, with batch-wise documentation and pan-India dispatch.

Interested in aceclofenac + paracetamol + chlorzoxazone tablets for your territory or your own brand? Enquire with Biozia Lifesciences →

Frequently asked questions

What is aceclofenac, paracetamol and chlorzoxazone used for?

It is used for musculoskeletal pain with muscle spasm, such as low back pain, neck pain, sprains and strains.

Does this tablet cause sleepiness?

Yes, chlorzoxazone can cause drowsiness or dizziness, so patients should avoid alcohol and driving until they know how it affects them.

Why does urine change colour on chlorzoxazone?

A harmless metabolite of chlorzoxazone can tint urine orange or reddish. It is not a sign of damage, but persistent dark urine with yellow eyes should be checked by a doctor.

Can I get this combination under my own brand?

Yes. Biozia offers Zianac-Forte for PCD franchise and can manufacture the same composition under your brand through third-party manufacturing.

This guide is for pharmacists, doctors, distributors and trade partners. It is general product information, not medical advice — patients should take any medicine only as prescribed by a registered medical practitioner.