Cholecalciferol 60,000 IU
| Composition | Cholecalciferol 60,000 IU |
|---|---|
| Packing | 10x1x4 Blister |
| MRP | ₹ 900 |
| Dosage Form | Capsules |
Exo-D3 Soft Gel Capsule contains Cholecalciferol 60,000 IU — a high-dose weekly supplementation form of Vitamin D3, the most bioavailable form of Vitamin D, designed to rapidly replenish Vitamin D deficiency.
Vitamin D3 plays a critical role in calcium absorption, bone health, immune function, and overall well-being. Exo-D3 is typically prescribed as a once-weekly or fortnightly supplement to efficiently restore adequate Vitamin D levels.
This medicine is commonly used for:
Cholecalciferol 60,000 IU is indicated for the prevention and treatment of Vitamin D deficiency states including nutritional rickets, osteomalacia, and as an adjunct in the management of osteoporosis. It is also indicated for supplementation in populations at high risk of Vitamin D deficiency including elderly individuals, those with limited sun exposure, and individuals with malabsorption syndromes.
When absorbed, Cholecalciferol is converted by the liver and kidneys into the active hormone Calcitriol, which acts throughout the body to improve calcium and phosphorus absorption from food, maintain bone mineralisation, support muscle function, and regulate immune responses. Exo-D3's high-dose format effectively builds up depleted Vitamin D stores.
Cholecalciferol (Vitamin D3) undergoes hepatic 25-hydroxylation to form 25-hydroxyvitamin D (calcidiol), followed by renal 1-alpha-hydroxylation to form the active metabolite 1,25-dihydroxyvitamin D3 (calcitriol). Calcitriol binds to the nuclear Vitamin D receptor (VDR), forming a complex with the retinoid X receptor (RXR) that regulates transcription of genes involved in intestinal calcium and phosphorus transport (TRPV6, calbindin), renal calcium reabsorption, and bone remodelling. VDR is also expressed in immune cells, skeletal muscle, and numerous other tissues, accounting for Vitamin D's pleiotropic physiological roles.
India has a paradoxically high prevalence of Vitamin D deficiency despite abundant sunshine — largely due to darker skin pigmentation (which requires more sun exposure to synthesise equivalent Vitamin D), traditional clothing, indoor lifestyles, and air pollution blocking UV-B rays.
Exo-D3 Soft Gel Capsule is typically prescribed as a once-weekly dose taken with a meal containing some fat, as Vitamin D3 is fat-soluble and absorbs better with dietary fat. Always follow your doctor's prescription regarding frequency and duration.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
When taken as prescribed, Cholecalciferol 60,000 IU is generally safe and well tolerated. Excessive supplementation beyond recommended levels over prolonged periods can cause Vitamin D toxicity with symptoms like nausea, excessive thirst, and elevated calcium levels. Tell your doctor if any side effect is severe or persistent.
If you live in a sunny country, you cannot be Vitamin D deficient.
Vitamin D deficiency is extremely common in India and other sun-rich countries. Factors like skin tone, clothing habits, sun avoidance, and urban lifestyles mean many people do not synthesise adequate Vitamin D despite ample sunshine.
More Vitamin D is always better.
Vitamin D is fat-soluble and accumulates in the body — excessive supplementation can cause toxicity with dangerously elevated calcium levels. Always follow the dose and frequency prescribed by your doctor.
Vitamin E 400 IU + Wheat germ Oil 100 mg + Omega 3 Fatty Acids 30 mg
Calcitrol IP 0.25 mcg + omega-3-fatty-acids containing Eicosapentaenoic acid 180 mg + Docosahexaenoic acid 120 mg + Folic acid 400 mcg + Methylcobalamine IP 1500 mcg + Boron 1.5 mg + calcium carbonate 500 mg
Rabeprazole 20 mg + Domperidone 30 mg(Sustained Release)
Omega 3 Fatty Acids Providing Eicosapentaenoic acid 90mg + Docosahexaenoic acid 60 mg + L-Methylfolate 1 mg + Vit K27 45 mcg + Methylcobalamine 1500 mcg, Pyridoxal-5-Phosphate 0.5 mg + Lycopene (6%) USP 10000mcg, Calcium Citrate USP 500 mg + Calcitriol IP 0.25 mcg, Magnesium Sulphate IP 50 mg