Ziacal-D3 Max Soft Gel Capsule
Calcitrol IP 0.25 mcg + omega-3-fatty-acids containing Eicosapentaenoic acid 180 mg + Docosahexaenoic acid 120 mg + Folic acid 400 mcg + Methylcobalamine IP 1500 mcg + Boron 1.5 mg + calcium carbonate 500 mg
| Composition | Calcitrol IP 0.25 mcg + omega-3-fatty-acids containing Eicosapentaenoic acid 180 mg + Docosahexaenoic acid 120 mg + Folic acid 400 mcg + Methylcobalamine IP 1500 mcg + Boron 1.5 mg + calcium carbonate 500 mg |
|---|---|
| Packing | 10x10 Blister |
| MRP | ₹ 2900 |
| Dosage Form | Capsules |
About Ziacal-D3 Max Soft Gel Capsule
Ziacal-D3 Max Soft Gel Capsule is a comprehensive bone and cardiovascular health supplement containing Calcitriol 0.25 mcg, Omega-3 Fatty Acids (EPA 180 mg + DHA 120 mg), Folic Acid 400 mcg, Methylcobalamin 1500 mcg, Boron 1.5 mg, and Calcium Carbonate 500 mg. This carefully formulated combination addresses the multiple nutritional requirements for maintaining strong, healthy bones while simultaneously supporting cardiovascular and nerve health.
Ziacal-D3 Max is designed to go beyond basic calcium supplementation by including Calcitriol (the active form of Vitamin D3) for superior calcium absorption, Omega-3 fatty acids for bone and heart health, Methylcobalamin and Folic Acid for nerve function, and Boron — a trace mineral that plays an important supporting role in calcium and bone metabolism.
Uses of Ziacal-D3 Max Soft Gel Capsule
This medicine is commonly used for:
- Supporting bone strength and reducing the risk of bone loss
- Nutritional support for osteopenia and osteoporosis management
- Calcium and Vitamin D supplementation during pregnancy and lactation
- Cardiovascular health support with Omega-3 EPA and DHA
- Nerve health and homocysteine support with Methylcobalamin and Folic Acid
Indications
Ziacal-D3 Max Soft Gel is indicated as a nutritional supplement for the support of bone mineral density through synergistic calcium and Vitamin D3 (Calcitriol) action, augmented by Boron, which enhances mineral retention and bone metabolism. Omega-3 EPA and DHA support cardiovascular health and possess anti-inflammatory properties relevant to bone remodeling. Methylcobalamin and Folic Acid support peripheral nerve health and homocysteine metabolism. Indicated as an adjunct nutritional support in osteopenia, osteoporosis, pregnancy, lactation, and general bone health maintenance.
How Ziacal-D3 Max Soft Gel Capsule Works
Ziacal-D3 Max supports bone health through multiple simultaneous pathways. Calcitriol (active Vitamin D3) opens the gut's calcium-absorption channels so more calcium from the supplement and diet gets into the bloodstream. Calcium Carbonate provides the raw mineral needed to build and maintain bone density. Boron helps retain calcium and magnesium in the bone. Omega-3 EPA and DHA reduce inflammation that can contribute to bone breakdown. Methylcobalamin and Folic Acid protect nerves and support healthy homocysteine levels, which when elevated can negatively affect bone.
Mechanism of Action
Calcitriol (1,25-dihydroxycholecalciferol) binds the nuclear Vitamin D receptor (VDR), upregulating the expression of calbindin and TRPV6 calcium channels in intestinal epithelial cells to enhance transcellular calcium absorption. Calcium Carbonate dissociates to provide ionized calcium for bone matrix mineralization and osteocalcin activation. Boron inhibits enzymes that degrade steroid hormones and Vitamin D, extending their activity; it also modulates magnesium and calcium metabolism. Omega-3 fatty acids (EPA/DHA) reduce RANKL-mediated osteoclast differentiation and inhibit pro-inflammatory prostaglandins that accelerate bone resorption. Methylcobalamin and Folic Acid support homocysteine remethylation — elevated homocysteine impairs collagen cross-linking in bone matrix. Together, these constituents address mineral supply, absorption, retention, anti-inflammatory bone protection, and structural matrix integrity.
Key Benefits
- Calcitriol maximizes calcium absorption from the gut — beyond what plain Vitamin D3 supplements achieve
- Multi-pathway bone support: calcium supply + absorption + retention + anti-inflammatory protection
- Omega-3s provide cardiovascular and anti-inflammatory bone protection
- Methylcobalamin and Folic Acid support nerve health alongside bone nutrition
Did You Know?
Boron is a trace mineral that was not recognized as nutritionally important in humans until relatively recently. Research has shown it helps reduce urinary calcium loss, modulates Vitamin D metabolism, and supports the hormonal environment needed for healthy bone maintenance — a small but mighty contributor to skeletal health.
When & How to Take
Ziacal-D3 Max Soft Gel is generally taken once daily with a meal, as directed by your doctor. Taking it with food that contains some fat improves absorption of Calcitriol and Omega-3 fatty acids. Always follow your doctor's prescribed dosage — do not self-adjust the dose.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Ziacal-D3 Max is generally well tolerated. Calcium supplements may occasionally cause mild constipation or bloating. A slight fishy aftertaste from Omega-3s may occur. Excess Calcitriol or Calcium beyond prescribed levels can cause hypercalcemia — always use as directed. Tell your doctor if any side effect is severe or persistent.
Precautions & Safety
- Do not exceed the prescribed dose — Calcitriol requires careful dosing to avoid hypercalcemia
- Inform your doctor if you have kidney stones or kidney disease before taking calcium and Calcitriol
- Regular monitoring of blood calcium levels may be needed with long-term Calcitriol supplementation
- Calcium Carbonate is best absorbed when taken with meals as it requires stomach acid
- Inform your doctor about all other supplements containing Vitamin D or Calcium to avoid duplication
Myths vs Facts
Plain Vitamin D3 tablets and Calcitriol are the same thing.
They are not. Vitamin D3 (cholecalciferol) must first be processed by the liver and then the kidneys to become Calcitriol, the active hormone form. People with kidney disease or certain other conditions cannot convert Vitamin D3 adequately. Ziacal-D3 Max provides Calcitriol directly — the active form — for reliable effect.
Calcium supplements are only important for the elderly.
Calcium and Vitamin D are important throughout life — during growth in children, in adults to maintain bone density, and especially in women during pregnancy, lactation, and after menopause. Building and protecting bone mass earlier in life also reduces osteoporosis risk later.
