Albozen-I Suspension
Albendazole 200 mg + Ivermectin 1.5 mg
| Composition | Albendazole 200 mg + Ivermectin 1.5 mg |
|---|---|
| Packing | 10ML |
| MRP | ₹ 35 |
| Dosage Form | Syrups & Suspensions |
About Albozen-I Suspension
Albozen-I Suspension is a dual antiparasitic suspension combining Albendazole 200 mg and Ivermectin 1.5 mg. This combination targets a wider spectrum of intestinal and tissue parasites than either drug alone — Albendazole disrupts worm energy metabolism while Ivermectin paralyses the worm's nervous system — making it a comprehensive deworming treatment.
Biozia Lifesciences' Albozen-I Suspension is used for mixed parasitic worm infections and provides a practical, easy-to-administer combination option for both adults and children requiring broader antiparasitic coverage.
Uses of Albozen-I Suspension
This medicine is commonly used for:
- Treating mixed intestinal worm infections (roundworm, hookworm, whipworm, pinworm)
- Managing strongyloidiasis (a type of roundworm infection that can be particularly persistent)
- Treating infections with both nematodes and organisms susceptible to Ivermectin
- Broader antiparasitic coverage when single-agent therapy is insufficient
- Deworming programmes targeting multiple worm types simultaneously
Indications
Indicated for the treatment of mixed helminth infections and specifically for strongyloidiasis (Strongyloides stercoralis), enterobiasis, ascariasis, ancylostomiasis, and trichuriasis where broader coverage including Ivermectin-sensitive parasites is required. The combination is also indicated where Albendazole alone may have reduced efficacy against certain parasitic species, and in areas with mixed parasitic infections requiring a broader anthelmintic spectrum. Particularly useful in regions endemic for multiple soil-transmitted helminths.
How Albozen-I Suspension Works
Albozen-I works through two different and complementary mechanisms. Albendazole cuts off the worm's energy supply by blocking glucose absorption, causing parasites to starve and die. Ivermectin, on the other hand, disrupts the worm's nervous system — causing paralysis so the worm can no longer move, feed, or reproduce. Together, they attack worms from two different angles, making treatment more thorough and effective against a broader range of parasites.
Mechanism of Action
Albendazole inhibits beta-tubulin polymerisation in helminth cells, disrupting microtubule-dependent glucose uptake and reducing intracellular ATP. Ivermectin selectively binds to glutamate-gated chloride ion channels (GluCl) in invertebrate nerve and muscle cells (absent in mammals), causing increased chloride ion permeability, hyperpolarisation, and irreversible paralysis of the parasite's pharyngeal and locomotor muscles. Ivermectin also potentiates GABA-gated chloride channels in invertebrates. The combination provides dual-target antiparasitic action: metabolic inhibition (Albendazole) and neuromuscular paralysis (Ivermectin), resulting in broader coverage and improved clearance of mixed helminth infections.
Key Benefits
- Dual-mechanism action targets parasites through both energy disruption and neuromuscular paralysis
- Broader spectrum than either drug alone — effective against mixed worm infections
- Suspension form is convenient for children and those unable to take tablets
- Comprehensive antiparasitic coverage in a single combined product
Did You Know?
Ivermectin — one of the active ingredients in Albozen-I — was awarded the Nobel Prize in Physiology or Medicine in 2015 for its transformative impact on tropical parasitic diseases. It has helped protect hundreds of millions of people from river blindness and other debilitating worm infections.
When & How to Take
Albozen-I Suspension should be taken as prescribed by your doctor. It is typically given as a single dose or a short course depending on the type of infection. Fasting before the dose or taking it with a small meal may be advised by your doctor. Always follow the prescribed instructions.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Common side effects may include mild nausea, stomach discomfort, diarrhoea, or dizziness. A transient worsening of skin itching (pruritus) may sometimes occur, particularly in patients with high worm burdens (due to dying parasites). Tell your doctor if any side effect is severe or persistent.
Precautions & Safety
- Not recommended during pregnancy or breastfeeding without clear medical guidance
- Use with caution in children under 5 years and only under medical supervision
- Patients with conditions affecting the central nervous system should use Ivermectin with caution
- Inform your doctor if you have liver disease, as both drugs are metabolised hepatically
- In patients with heavy Loa loa (eye worm) burden, Ivermectin should be used with extreme caution — discuss with your doctor if you have been in regions where this parasite is endemic
Myths vs Facts
Combination deworming products are more dangerous than single-ingredient ones.
Albendazole and Ivermectin have established safety profiles and are used together in WHO-recommended mass drug administration programmes worldwide. The combination is well tolerated at prescribed doses.
A single dose of antiparasitic suspension will protect you from worm infections permanently.
Antiparasitic medicines treat active infections but do not prevent future reinfection. Good hygiene, sanitation, and periodic deworming (as recommended by a doctor or public health guidelines) are key to long-term protection.
