ZiaLact Solution (S/F)
Lactulose 10 gm
| Composition | Lactulose 10 gm |
|---|---|
| Packing | 200ML |
| MRP | ₹ 280 |
| Dosage Form | Syrups & Suspensions |
About ZiaLact Solution (S/F)
ZiaLact Solution (Sugar-Free) contains Lactulose 10 gm per dose, a well-established osmotic laxative used to treat constipation and hepatic encephalopathy by drawing water into the bowel to soften stools and promote comfortable bowel movements.
Biozia's ZiaLact Solution is available in a sugar-free formulation, making it suitable for diabetic patients. It is gentle on the gut and acts without being absorbed into the bloodstream, making Lactulose one of the safest laxatives for long-term use when prescribed.
Uses of ZiaLact Solution (S/F)
This medicine is commonly used for:
- Relief from chronic and occasional constipation
- Softening stools for easier, more comfortable bowel movements
- Management of hepatic encephalopathy (a liver complication involving brain function)
- Post-operative bowel management where straining must be avoided
- Constipation in elderly patients and children (under medical guidance)
Indications
Lactulose solution is indicated for the treatment of chronic constipation and as an adjunct in the management of hepatic (portal-systemic) encephalopathy, including the prevention and treatment of episodes of hepatic coma and precoma. In the context of hepatic encephalopathy, Lactulose acidifies the colonic contents to reduce colonic generation of ammonia and facilitates its excretion, reducing blood ammonia levels.
How ZiaLact Solution (S/F) Works
Lactulose is a synthetic sugar that the body cannot digest or absorb. When it reaches the large intestine, it draws water into the bowel by osmosis, softening the stool and making it easier to pass. Gut bacteria also ferment Lactulose, producing mild acids that further soften stools and stimulate bowel movement. In liver disease, this same acidifying effect helps trap and remove ammonia from the gut before it can reach the blood.
Mechanism of Action
Lactulose (a synthetic disaccharide of galactose and fructose) is not hydrolysed by intestinal disaccharidases and reaches the colon intact. Colonic bacteria metabolise lactulose to short-chain fatty acids (lactic, acetic, formic) and CO2, lowering luminal pH and increasing osmotic pressure. The osmotic effect draws water into the colonic lumen, increasing stool water content and promoting peristalsis. In hepatic encephalopathy, the acidic environment converts ammonia (NH3) to the non-absorbable ammonium ion (NH4+), reducing colonic ammonia absorption and lowering systemic blood ammonia levels. It also reduces colonic transit time, decreasing overall ammonia production.
Key Benefits
- Gentle, effective relief from constipation without habit-forming effects
- Sugar-free formulation safe for diabetic patients
- Works locally in the gut without systemic absorption, making it safe for most patients
- Dual benefit: relieves constipation and reduces ammonia in liver disease management
Did You Know?
Lactulose was first developed in the 1950s as a synthetic sugar and was initially studied for infant nutrition. Its unique property of being entirely undigested by the human gut led to its use as a safe laxative and later as a cornerstone treatment for hepatic encephalopathy in patients with liver disease.
When & How to Take
ZiaLact Solution should be taken as directed by your doctor, usually once or twice daily. It can be mixed with water, juice, or other beverages. Results in constipation may take 24–48 hours — do not increase the dose prematurely. Drink plenty of water throughout the day.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Initial use may cause bloating, gas, stomach cramps, or a feeling of fullness as the gut adjusts. These effects usually subside with continued use. Diarrhoea may occur if the dose is too high. Tell your doctor if any side effect is severe or persistent.
Precautions & Safety
- Inform your doctor if you are lactose intolerant or have galactosaemia, as Lactulose contains galactose and may not be suitable
- Maintain adequate hydration while using this solution to support its laxative effect
- Do not use for more than a few days without medical guidance unless prescribed for a chronic condition
- Avoid use in patients with intestinal obstruction
- In diabetic patients, the sugar-free formulation is preferred — always inform your doctor about your diabetes
Myths vs Facts
Lactulose is a regular sugar and will raise blood sugar levels.
Lactulose is a synthetic disaccharide that is not absorbed by the human gut. In the sugar-free formulation, it does not cause the blood sugar spikes associated with regular sugars, making it suitable for use in diabetic patients.
Laxatives cause the body to become dependent on them and stop working on their own.
Osmotic laxatives like Lactulose work differently from stimulant laxatives and are not associated with the same degree of dependence. However, long-term use should always be under medical supervision to address any underlying cause of constipation.
