Calcium Carbonate, Vitamin K2-7 & Calcitriol Tablets: Uses & Benefits

Reviewed by Anil Kumar Goel, B.Pharm — Chairman, Biozia Lifesciences, 40+ years in the pharmaceutical industry.

Calcium supplements with vitamin K2-7 and calcitriol are increasingly prescribed for bone health because they combine calcium with the vitamins that help direct it into bone. This guide explains what each ingredient does, who the supplement is for, how to take it, and how Biozia supplies it as Ziacal-K27 Tablet.

Key takeaways (TL;DR)

Combines Calcium Carbonate 1250 mg (500 mg elemental calcium), Vitamin K2-7, Calcitriol, Folic Acid, Zinc, Magnesium and Boron.
Used for osteoporosis and osteopenia, calcium deficiency, and bone support in women, older adults and during fracture healing.
Calcium carbonate is a concentrated calcium source and is best absorbed when taken with a meal.
Calcitriol is active vitamin D, so calcium levels may need monitoring with long-term use.
Biozia supplies Ziacal-K27 (10×10 Alu/Alu) for PCD franchise and third-party manufacturing.

Composition

Biozia manufactures this bone-health formulation as:

Brand	Composition	Packing
Ziacal-K27 Tablet	Vitamin K27 100 mcg + Calcium Carbonate 1250 mg (eq. to elemental Calcium 500 mg) + Calcitriol 0.25 mcg + Folic Acid 5 mg + Zinc 7.5 mg + Magnesium Hydroxide 50 mg + Sodium Borate 100 mcg	10×10 Alu/Alu

What each ingredient does

Calcium carbonate — a concentrated source of elemental calcium (40% by weight) for bone mineralisation.
Calcitriol — the active form of vitamin D, which increases calcium absorption from the gut.
Vitamin K2-7 (menaquinone-7) — activates osteocalcin, which binds calcium into the bone matrix.
Magnesium, zinc and boron — trace minerals that support bone formation and vitamin D metabolism.
Folic acid — supports red blood cell formation and is often needed alongside calcium in women.

Uses

Osteoporosis and osteopenia
Calcium and vitamin D deficiency
Bone support after menopause and in older adults
Fracture healing, as prescribed
Pregnancy and breastfeeding, when prescribed by a doctor

How to take

Take as prescribed, usually one tablet a day with a meal — calcium carbonate needs stomach acid to dissolve, so it is absorbed best with food. Keep a gap of two to four hours from iron supplements, thyroid medicine (levothyroxine) and antibiotics such as tetracyclines and fluoroquinolones, because calcium reduces their absorption.

Side effects and precautions

Constipation, bloating and nausea are the most common effects.

Not for people with high blood calcium, vitamin D toxicity or calcium-containing kidney stones.
Because it contains calcitriol, avoid combining with other vitamin D or calcium supplements unless advised; calcium levels may be checked during long-term use.
Patients on warfarin should consult their doctor, as vitamin K can affect anticoagulation.
Use with caution in kidney disease.

For distributors: PCD franchise and third-party manufacturing

Bone-health supplements are a steadily growing category, prescribed by orthopaedic surgeons, gynaecologists and physicians for long-term use. A calcium + vitamin K2-7 + calcitriol formulation like Ziacal-K27 complements Biozia’s Ziacal calcium suspension for franchise partners serving the women’s-health and ortho segments.

PCD franchise — stock Ziacal-K27 under monopoly rights in your district. See PCD pharma franchise with Biozia.
Third-party manufacturing — get this formulation made under your own brand name. See third-party manufacturing services.
Quality — WHO-GMP and ISO certified manufacturing in Yamunanagar, Haryana, with batch-wise documentation and pan-India dispatch.

Interested in calcium + vitamin K2-7 tablets for your territory or your own brand? Enquire with Biozia Lifesciences →

Frequently asked questions

What is calcium carbonate with vitamin K2-7 and calcitriol used for?

It is used for bone health — osteoporosis, osteopenia, calcium deficiency and bone support during ageing, after menopause and during fracture healing.

Why is vitamin K2-7 added to calcium tablets?

Vitamin K2-7 activates proteins that help bind calcium into bone, so the calcium supports the skeleton more effectively.

When is the best time to take this calcium tablet?

Usually once a day with a meal, kept two to four hours apart from iron, thyroid medicine and certain antibiotics.

Is Ziacal-K27 available for PCD franchise?

Yes. Ziacal-K27 is available for PCD franchise and similar bone-health formulations can be manufactured under your own brand.

This guide is for pharmacists, doctors, distributors and trade partners. It is general product information, not medical advice — patients should take any medicine only as prescribed by a registered medical practitioner.