Diclofenac, Chlorzoxazone & Paracetamol (Diclo MR) Tablets: Uses

Reviewed by Anil Kumar Goel, B.Pharm — Chairman, Biozia Lifesciences, 40+ years in the pharmaceutical industry.

“Diclo MR” tablets combine diclofenac, the muscle relaxant chlorzoxazone and paracetamol, and are one of the most familiar prescriptions for painful muscle spasm and back pain in India. This guide explains the combination, its uses, dosing and safety, and how Biozia supplies it as Dicrex-MR Tablet.

Key takeaways (TL;DR)

Each tablet contains Diclofenac Potassium 50 mg, Chlorzoxazone 250 mg and Paracetamol 325 mg.
“MR” here means muscle relaxant, not modified release.
Used for back pain, neck pain, sprains and other painful muscle spasm.
Usually one tablet two to three times a day after food, short-term, as prescribed.
Biozia supplies Dicrex-MR (10×10 blister) for PCD franchise and third-party manufacturing.

Composition and available strengths

Biozia manufactures this combination as:

Brand	Composition	Packing
Dicrex-MR Tablet	Diclofenac Potassium 50 mg + Chlorzoxazone 250 mg + Paracetamol 325 mg	10×10 Blister

How it works

Diclofenac potassium is a fast-acting NSAID that reduces pain and inflammation. Chlorzoxazone relaxes skeletal muscle spasm through its action on the spinal cord. Paracetamol adds central pain relief. The potassium salt of diclofenac is absorbed quickly, which suits acute pain.

Uses

Acute low back pain, neck pain and stiff neck
Muscle spasm after sprains, strains or injury
Painful musculoskeletal conditions with spasm
Post-traumatic pain and swelling

Dosage

The usual adult dose is one tablet two to three times a day after meals, for the shortest period needed. Do not take with other NSAIDs or paracetamol-containing products.

Side effects

Common effects include acidity, nausea, stomach pain, drowsiness and dizziness. Chlorzoxazone may colour the urine orange or reddish, which is harmless. NSAIDs such as diclofenac can rarely cause stomach bleeding, kidney problems and an increased risk of heart attack or stroke, especially with high doses or long use.

Precautions and contraindications

Avoid with active peptic ulcer, gastrointestinal bleeding, or NSAID allergy (including aspirin-induced asthma).
Not for people with heart failure, ischaemic heart disease or stroke history, or severe liver or kidney disease.
Avoid alcohol; it raises drowsiness and liver risk.
Avoid in the third trimester of pregnancy and use earlier only on medical advice.

For distributors: PCD franchise and third-party manufacturing

Diclofenac-based muscle relaxant tablets are among the highest-volume orthopaedic prescriptions in Indian clinics and pharmacies. Dicrex-MR fits alongside Zianac-Forte and the Ziacox etoricoxib range, giving franchise partners a full pain and spasm portfolio.

PCD franchise — stock Dicrex-MR under monopoly rights in your district. See PCD pharma franchise with Biozia.
Third-party manufacturing — get this formulation made under your own brand name. See third-party manufacturing services.
Quality — WHO-GMP and ISO certified manufacturing in Yamunanagar, Haryana, with batch-wise documentation and pan-India dispatch.

Interested in diclofenac MR tablets for your territory or your own brand? Enquire with Biozia Lifesciences →

Frequently asked questions

What does MR mean in Diclo MR tablets?

MR stands for muscle relaxant. The tablet contains chlorzoxazone, a muscle relaxant, along with diclofenac and paracetamol.

What is diclofenac, chlorzoxazone and paracetamol used for?

It is used for painful muscle spasm, such as back pain, neck pain, sprains and strains.

Can Diclo MR tablets make you sleepy?

Yes, chlorzoxazone can cause drowsiness, so avoid alcohol and driving if affected.

Is Dicrex-MR available for PCD franchise?

Yes. Dicrex-MR is available for PCD franchise and the same formulation can be manufactured under your own brand.

This guide is for pharmacists, doctors, distributors and trade partners. It is general product information, not medical advice — patients should take any medicine only as prescribed by a registered medical practitioner.