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NSAID Analgesic & Anti-Inflammatory (Injection)

DICREX 1ml Injection

Diclofenac Sodium 75 mg

Composition Diclofenac Sodium 75 mg
Packing 1ml
MRP ₹ 15
Dosage Form Injections

About DICREX 1ml Injection

DICREX 1ml Injection is a potent injectable formulation of Diclofenac Sodium 75 mg, a widely used non-steroidal anti-inflammatory drug (NSAID). It is administered when fast-acting pain relief and reduction of inflammation are required and oral medication is not suitable or sufficient.

Biozia Lifesciences' DICREX Injection is used in clinical and hospital settings to quickly manage moderate to severe pain from musculoskeletal conditions, postoperative pain, renal colic, and other acute inflammatory conditions.

Uses of DICREX 1ml Injection

This medicine is commonly used for:

  • Fast relief of acute moderate to severe pain and inflammation
  • Managing pain from muscle injuries, sprains, and joint conditions
  • Relief of postoperative pain
  • Acute pain from kidney stones (renal colic)
  • Short-term management of migraine attacks with inflammatory component

Indications

Indicated for the acute short-term treatment of moderate to severe pain including postoperative pain, renal or biliary colic, acute musculoskeletal pain and trauma, acute exacerbations of osteoarthritis and rheumatoid arthritis, and acute attacks of gout. Parenteral diclofenac sodium is used when rapid onset of analgesia is required and the oral route is impractical.

How DICREX 1ml Injection Works

DICREX works by blocking the production of certain natural chemicals in the body called prostaglandins, which are responsible for causing pain, swelling, and fever. By reducing prostaglandin production quickly through injection, DICREX provides rapid relief from pain and inflammation at the site of injury or inflammation.

Mechanism of Action

Diclofenac sodium is a potent non-selective inhibitor of cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, prostacyclin, and thromboxane from arachidonic acid. The reduction in prostaglandin E2 and I2 at peripheral nociceptors decreases sensitisation of pain receptors. Intramuscular administration results in rapid peak plasma concentrations (within 20–40 minutes), providing faster onset of analgesia compared to oral formulations.

Key Benefits

  • Rapid onset of pain relief through injectable delivery
  • Effectively reduces both pain and inflammation simultaneously
  • Useful when oral medication cannot be taken (e.g., post-surgery or severe nausea)
  • Short treatment course minimises prolonged NSAID exposure

Did You Know?

Diclofenac is one of the most widely prescribed NSAIDs in the world and is on the World Health Organization's List of Essential Medicines, highlighting its importance in managing pain globally.

When & How to Take

DICREX 1ml Injection is given as an intramuscular injection by a healthcare professional, as prescribed by your doctor. It is intended for short-term use only. The number of injections and the duration of treatment are decided by your doctor based on your condition.

Always follow the dosage and schedule advised by your doctor — this is general guidance only.

Possible Side Effects

Common side effects may include pain or tenderness at the injection site, mild nausea, stomach discomfort, or dizziness. In some cases, it may affect kidney function or cause elevated liver enzymes with prolonged use. Tell your doctor if any side effect is severe or persistent.

Precautions & Safety

  • Not recommended for patients with a known allergy to diclofenac, aspirin, or other NSAIDs
  • Use with caution in patients with a history of peptic ulcer, kidney disease, or heart conditions
  • Avoid in the third trimester of pregnancy
  • Inform your doctor about all other medications, especially blood thinners or other NSAIDs
  • Intended for short-term use only; prolonged use should be under strict medical supervision

Myths vs Facts

Myth

Diclofenac injections are completely safe because they bypass the stomach.

Fact

While injections avoid direct stomach irritation, diclofenac still reduces prostaglandins that protect the stomach lining. Gastrointestinal side effects can still occur, especially with prolonged use.

Myth

NSAID injections can be given as frequently as needed without risk.

Fact

NSAIDs like diclofenac are recommended for short-term use. Frequent or long-term use increases the risk of kidney, liver, and cardiovascular side effects.

Frequently Asked Questions

It is used to provide fast relief from moderate to severe pain and inflammation, including postoperative pain, renal colic, and acute musculoskeletal pain.
Being an injection, it typically begins to work within 20 to 40 minutes, providing faster relief than oral tablets.
It should be used with caution or avoided in patients with kidney disease. Your doctor will assess your kidney function before prescribing it.
It should be avoided during the third trimester of pregnancy. Consult your doctor before using it at any stage of pregnancy.
Medical disclaimer: This information is for general awareness and education only and is not a substitute for professional medical advice. DICREX 1ml Injection is a pharmaceutical product to be used only as prescribed by a registered medical practitioner. Always read the package insert and consult your doctor or pharmacist before use. Biozia Lifesciences markets this product to licensed pharmacy and healthcare businesses.

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