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Vitamin D3 Supplement (Cholecalciferol)

Exo-D3 Soft Gel Capsule

Cholecalciferol 60,000 IU

Composition Cholecalciferol 60,000 IU
Packing 10x1x4 Blister
MRP ₹ 900
Dosage Form Capsules

About Exo-D3 Soft Gel Capsule

Exo-D3 Soft Gel Capsule contains Cholecalciferol 60,000 IU — a high-dose weekly supplementation form of Vitamin D3, the most bioavailable form of Vitamin D, designed to rapidly replenish Vitamin D deficiency.

Vitamin D3 plays a critical role in calcium absorption, bone health, immune function, and overall well-being. Exo-D3 is typically prescribed as a once-weekly or fortnightly supplement to efficiently restore adequate Vitamin D levels.

Uses of Exo-D3 Soft Gel Capsule

This medicine is commonly used for:

  • Correction of Vitamin D deficiency and insufficiency
  • Supporting bone health and calcium absorption
  • Reducing risk of bone loss (osteoporosis) and bone softening (osteomalacia/rickets)
  • Supporting immune system function
  • Complementary support in musculoskeletal pain linked to low Vitamin D

Indications

Cholecalciferol 60,000 IU is indicated for the prevention and treatment of Vitamin D deficiency states including nutritional rickets, osteomalacia, and as an adjunct in the management of osteoporosis. It is also indicated for supplementation in populations at high risk of Vitamin D deficiency including elderly individuals, those with limited sun exposure, and individuals with malabsorption syndromes.

How Exo-D3 Soft Gel Capsule Works

When absorbed, Cholecalciferol is converted by the liver and kidneys into the active hormone Calcitriol, which acts throughout the body to improve calcium and phosphorus absorption from food, maintain bone mineralisation, support muscle function, and regulate immune responses. Exo-D3's high-dose format effectively builds up depleted Vitamin D stores.

Mechanism of Action

Cholecalciferol (Vitamin D3) undergoes hepatic 25-hydroxylation to form 25-hydroxyvitamin D (calcidiol), followed by renal 1-alpha-hydroxylation to form the active metabolite 1,25-dihydroxyvitamin D3 (calcitriol). Calcitriol binds to the nuclear Vitamin D receptor (VDR), forming a complex with the retinoid X receptor (RXR) that regulates transcription of genes involved in intestinal calcium and phosphorus transport (TRPV6, calbindin), renal calcium reabsorption, and bone remodelling. VDR is also expressed in immune cells, skeletal muscle, and numerous other tissues, accounting for Vitamin D's pleiotropic physiological roles.

Key Benefits

  • High-dose formulation rapidly corrects Vitamin D deficiency
  • Supports calcium absorption for stronger bones and reduced fracture risk
  • Soft gel capsule provides better absorption than powder-based formulations
  • Supports immune health, muscle function, and general well-being

Did You Know?

India has a paradoxically high prevalence of Vitamin D deficiency despite abundant sunshine — largely due to darker skin pigmentation (which requires more sun exposure to synthesise equivalent Vitamin D), traditional clothing, indoor lifestyles, and air pollution blocking UV-B rays.

When & How to Take

Exo-D3 Soft Gel Capsule is typically prescribed as a once-weekly dose taken with a meal containing some fat, as Vitamin D3 is fat-soluble and absorbs better with dietary fat. Always follow your doctor's prescription regarding frequency and duration.

Always follow the dosage and schedule advised by your doctor — this is general guidance only.

Possible Side Effects

When taken as prescribed, Cholecalciferol 60,000 IU is generally safe and well tolerated. Excessive supplementation beyond recommended levels over prolonged periods can cause Vitamin D toxicity with symptoms like nausea, excessive thirst, and elevated calcium levels. Tell your doctor if any side effect is severe or persistent.

Precautions & Safety

  • Do not take additional Vitamin D supplements without medical advice, as excessive intake can cause toxicity
  • Inform your doctor of any history of kidney stones, hypercalcaemia, or granulomatous conditions like sarcoidosis
  • Periodic blood tests to monitor Vitamin D and calcium levels may be recommended during high-dose supplementation
  • Certain medications like corticosteroids or anticonvulsants can interfere with Vitamin D metabolism — inform your doctor
  • Store in a cool, dark place away from direct sunlight to preserve potency

Myths vs Facts

Myth

If you live in a sunny country, you cannot be Vitamin D deficient.

Fact

Vitamin D deficiency is extremely common in India and other sun-rich countries. Factors like skin tone, clothing habits, sun avoidance, and urban lifestyles mean many people do not synthesise adequate Vitamin D despite ample sunshine.

Myth

More Vitamin D is always better.

Fact

Vitamin D is fat-soluble and accumulates in the body — excessive supplementation can cause toxicity with dangerously elevated calcium levels. Always follow the dose and frequency prescribed by your doctor.

Frequently Asked Questions

It is used to supplement Vitamin D3 and correct deficiency — supporting bone health, calcium absorption, immune function, and overall nutritional balance.
High-dose Vitamin D3 is typically prescribed as once weekly or once fortnightly. Your doctor will determine the frequency and duration based on your Vitamin D levels from a blood test.
Yes — Vitamin D3 is fat-soluble, meaning it absorbs best when taken with a meal that contains some fat (such as a regular meal with dairy, nuts, or cooking oil).
A simple blood test measuring 25-hydroxy Vitamin D levels can confirm deficiency. Common symptoms include bone pain, fatigue, muscle weakness, and frequent infections — but many people have no obvious symptoms.
Medical disclaimer: This information is for general awareness and education only and is not a substitute for professional medical advice. Exo-D3 Soft Gel Capsule is a pharmaceutical product to be used only as prescribed by a registered medical practitioner. Always read the package insert and consult your doctor or pharmacist before use. Biozia Lifesciences markets this product to licensed pharmacy and healthcare businesses.

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