Coldrox Super Tablet
Aceclofenac 100 mg + Paracetamol 325 mg + Citrizine Dihydrochloride 10 mg + Phenylephrine HCL Caffeine (Anhydrous) 25mg
| Composition | Aceclofenac 100 mg + Paracetamol 325 mg + Citrizine Dihydrochloride 10 mg + Phenylephrine HCL Caffeine (Anhydrous) 25mg |
|---|---|
| Packing | 10X10 Blister |
| MRP | ₹ 799 |
| Dosage Form | Tablets |
About Coldrox Super Tablet
Coldrox Super Tablet is a comprehensive cold and flu symptom relief combination containing Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine Dihydrochloride 10 mg, Phenylephrine HCl, and Caffeine (Anhydrous) 25 mg. This powerful multi-ingredient formulation is designed for adults who need relief from cold symptoms that include significant pain, fever, nasal congestion, and allergic symptoms simultaneously.
Coldrox Super from Biozia Lifesciences steps up the pain-relieving component with aceclofenac — an NSAID — alongside paracetamol, offering more potent anti-inflammatory and analgesic support for when body aches and fever are more pronounced. Cetirizine, a second-generation antihistamine, replaces older first-generation options to reduce sneezing and runny nose with minimal drowsiness.
Uses of Coldrox Super Tablet
This medicine is commonly used for:
- Relieving body aches, joint pain, and headache during cold, flu, or fever
- Controlling nasal congestion and sinus pressure
- Reducing sneezing, watery eyes, and runny nose
- Managing fever associated with cold, flu, or mild infections
- Providing comprehensive multi-symptom cold relief in one tablet
Indications
This combination is indicated for symptomatic management of moderate pain and pyrexia with concomitant upper respiratory tract allergic/vasomotor symptoms. Aceclofenac provides analgesic and anti-inflammatory relief beyond that achievable with paracetamol alone; paracetamol augments analgesia and antipyresis; cetirizine dihydrochloride provides selective peripheral H1-receptor blockade for rhinorrhoea, sneezing, and nasal pruritus; phenylephrine HCl provides nasal mucosal decongestant action; and caffeine serves as an analgesic adjuvant and mild stimulant.
How Coldrox Super Tablet Works
Coldrox Super attacks cold symptoms on multiple fronts simultaneously. Aceclofenac and paracetamol work together to reduce pain, inflammation, and fever more effectively than either alone. Cetirizine blocks the histamine receptors responsible for sneezing and runny nose — and being a newer antihistamine, it causes much less drowsiness than older alternatives. Phenylephrine constricts swollen nasal blood vessels to open up blocked airways, while caffeine provides a gentle alertness boost.
Mechanism of Action
Aceclofenac is a phenylacetic acid NSAID that inhibits COX-1 and COX-2 enzymes, reducing peripheral prostaglandin synthesis and thereby attenuating inflammation, pain, and fever. Paracetamol exerts additional central analgesic and antipyretic effects via prostaglandin inhibition in the CNS and modulation of descending serotonergic pathways. Cetirizine is a piperazine-class selective peripheral H1-receptor antagonist with negligible CNS penetration, minimising sedation while effectively reducing histamine-mediated rhinorrhoea and sneezing. Phenylephrine acts as an alpha-1 adrenergic agonist to constrict nasal mucosal vasculature. Caffeine potentiates analgesic efficacy through adenosine receptor antagonism.
Key Benefits
- Superior pain and fever relief due to the combination of aceclofenac and paracetamol
- Non-drowsy antihistamine (cetirizine) controls runny nose and sneezing without excessive sedation
- Nasal decongestant action provides relief from blocked nose and sinus pressure
- All-in-one formulation reduces the need for multiple separate tablets
Did You Know?
Cetirizine, the antihistamine in Coldrox Super, was specifically developed as a second-generation antihistamine to maintain effective allergy control with far less sedation than earlier antihistamines like diphenhydramine. It achieves this by not crossing the blood-brain barrier in significant amounts.
When & How to Take
Coldrox Super should be taken as directed by your doctor, preferably with or after food to reduce the risk of stomach irritation from aceclofenac. Do not take on an empty stomach. Avoid combining with other NSAIDs, aspirin, or additional paracetamol-containing products. Follow your doctor's prescribed duration carefully.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Some patients may experience mild stomach discomfort, heartburn, nausea, or dizziness. Aceclofenac may occasionally cause gastrointestinal irritation; taking the tablet with food helps reduce this. Mild drowsiness may occur in some individuals. Tell your doctor if any side effect is severe or persistent, particularly any stomach pain or signs of allergic reaction.
Precautions & Safety
- Always take this medicine with food to protect the stomach lining from NSAID-related irritation
- Avoid use if you have a history of peptic ulcer, stomach bleeding, or severe kidney or liver disease
- Do not combine with other NSAIDs, aspirin, or blood-thinning medicines without medical advice
- Inform your doctor if you have high blood pressure, heart disease, or asthma before taking this tablet
- Not recommended for children, pregnant women, or breastfeeding mothers without a doctor's guidance
Myths vs Facts
Coldrox Super is a cure for the common cold.
No medicine cures the common cold, which is caused by viruses. Coldrox Super relieves symptoms like pain, congestion, and runny nose while your immune system fights the infection naturally.
Taking two NSAIDs together gives better pain relief.
Combining NSAIDs (e.g. taking another NSAID alongside aceclofenac) does not improve pain relief and significantly increases the risk of gastrointestinal bleeding and kidney problems. Always follow the prescribed single-medicine regimen.
