Zymozia Tablet
L-Ornithine L-Aspartate 150mg + Pancreatin 100mg
| Composition | L-Ornithine L-Aspartate 150mg + Pancreatin 100mg |
|---|---|
| Packing | 10x10 Strip Pack |
| MRP | ₹ 1020 |
| Dosage Form | Tablets |
About Zymozia Tablet
Zymozia Tablet combines L-Ornithine L-Aspartate 150 mg with Pancreatin 100 mg — a unique formulation that bridges liver metabolic support with digestive enzyme supplementation.
L-Ornithine L-Aspartate (LOLA) is a well-studied hepatoprotective compound used to support ammonia detoxification in liver conditions, while Pancreatin aids the digestion of nutrients, making this combination particularly relevant for patients with liver disease who commonly experience both impaired ammonia metabolism and digestive insufficiency.
Uses of Zymozia Tablet
This medicine is commonly used for:
- Supporting liver function in hepatic conditions
- Managing elevated ammonia levels associated with liver disease
- Aiding digestion in patients with liver-related digestive insufficiency
- Supportive nutrition in cirrhosis and chronic liver conditions
- Reducing hepatic encephalopathy-related symptoms (as adjunctive support)
Indications
Zymozia Tablet is indicated as nutritional and metabolic support in patients with hepatic insufficiency, particularly those with hyperammonaemia associated with cirrhosis or chronic hepatic conditions. L-Ornithine L-Aspartate supports urea cycle function and ammonia clearance. Pancreatin provides exocrine enzyme supplementation, addressing the secondary digestive impairment commonly seen in liver disease.
How Zymozia Tablet Works
L-Ornithine L-Aspartate supplies two amino acids — Ornithine and Aspartate — that the liver uses to convert toxic ammonia into the safer compound urea, which is then eliminated from the body. Pancreatin provides digestive enzymes that help break down food more efficiently, supporting better nutrition in patients whose digestion may be compromised.
Mechanism of Action
L-Ornithine serves as a substrate and activator of the urea cycle — it is converted to citrulline and then to arginine in the urea cycle, facilitating the conversion of ammonia to urea via hepatic carbamoyl phosphate synthetase activation. L-Aspartate participates in the malate-aspartate shuttle and the transamination reactions that detoxify ammonia in periportal and perivenous hepatocytes. Together, LOLA reduces circulating ammonia levels. Pancreatin's lipases, proteases, and amylases supplement deficient exocrine pancreatic secretion in liver disease, where secondary pancreatic insufficiency may occur.
Key Benefits
- Supports the liver's ammonia detoxification pathway, reducing ammonia build-up
- Addresses digestive insufficiency common in liver disease patients
- Provides metabolic and nutritional support in one combined formulation
- Well-established role of LOLA in hepatic metabolic support
Did You Know?
The liver performs over 500 different functions, including detoxifying ammonia produced by the breakdown of dietary proteins — an impaired liver's reduced ability to do this is one of the mechanisms behind hepatic encephalopathy, a condition LOLA is used to support.
When & How to Take
Zymozia Tablet should be taken as directed by your doctor, typically with or before meals. The dosing schedule in liver conditions is particularly important — always follow medical advice strictly.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Generally well tolerated. Some patients may experience mild nausea, abdominal discomfort, or loose stools, particularly at the start of treatment. These usually settle with time. Tell your doctor if any side effect is severe or persistent.
Precautions & Safety
- Use only under medical supervision, especially in patients with significant liver disease
- Inform your doctor of any kidney problems, as impaired ammonia excretion may require adjusted management
- Follow dietary and nutritional guidance from your doctor alongside supplementation
- Do not self-medicate for liver conditions — accurate diagnosis and monitoring are essential
- Inform your doctor of all other medications and supplements being taken
Myths vs Facts
Liver problems only affect people who drink alcohol excessively.
While alcohol is a common cause, liver conditions arise from many causes including viral hepatitis, fatty liver disease (NAFLD), autoimmune conditions, and medications. Liver support therapy may be needed in any of these situations.
Nutritional supplements can cure liver disease.
Supplements like L-Ornithine L-Aspartate support specific metabolic functions and nutritional status — they are an adjunct to medical treatment, not a cure for underlying liver conditions.
