Telvex-AM Tablet
Amlodipine 5 Mg + Telmisartan 40 Mg
| Composition | Amlodipine 5 Mg + Telmisartan 40 Mg |
|---|---|
| Packing | 10x10 Alu/Alu |
| MRP | ₹ 860 |
| Dosage Form | Tablets |
About Telvex-AM Tablet
Telvex-AM Tablet is a combination antihypertensive tablet containing Amlodipine 5 mg and Telmisartan 40 mg. It is prescribed to manage high blood pressure (hypertension) in patients whose blood pressure is not adequately controlled on a single medication. By combining two medicines that lower blood pressure through different mechanisms, Telvex-AM provides more effective and sustained blood pressure control.
Amlodipine relaxes the blood vessels by blocking calcium entry into vessel wall cells, while Telmisartan blocks the action of a hormone (angiotensin II) that causes blood vessels to constrict. Together in Telvex-AM, they offer complementary and additive blood pressure lowering with a well-established cardiovascular safety profile.
Uses of Telvex-AM Tablet
This medicine is commonly used for:
- Treatment of high blood pressure (hypertension)
- Management of blood pressure in patients needing combination therapy
- Reducing the risk of cardiovascular events in hypertensive patients
- Blood pressure control in patients with type 2 diabetes and hypertension
- Management of hypertension in patients with kidney disease (as prescribed)
Indications
Amlodipine-Telmisartan combination is indicated for the treatment of essential hypertension in adult patients whose blood pressure is not adequately controlled on either monotherapy. Telmisartan is also indicated for the reduction of cardiovascular morbidity in adults with established atherothrombotic cardiovascular disease or type 2 diabetes mellitus with documented target-organ damage. The combination provides additive antihypertensive efficacy with complementary mechanisms and a synergistic renal protective profile.
How Telvex-AM Tablet Works
Telmisartan in Telvex-AM blocks a natural hormone that makes blood vessels narrow, keeping them more relaxed and open. Amlodipine prevents calcium from entering the muscle cells of blood vessel walls, which also relaxes and widens the vessels. Both actions reduce the resistance that the heart has to pump against, lowering blood pressure and easing the workload on the heart.
Mechanism of Action
Telmisartan is a selective angiotensin II type 1 (AT1) receptor antagonist. By blocking AT1 receptors in vascular smooth muscle and the adrenal gland, it prevents angiotensin II-mediated vasoconstriction, aldosterone secretion, and sodium retention, producing vasodilation and natriuresis. Telmisartan also has partial peroxisome proliferator-activated receptor gamma (PPARγ) agonist activity, which may confer additional metabolic benefits. Amlodipine is a third-generation dihydropyridine calcium channel blocker that blocks L-type voltage-gated calcium channels in vascular smooth muscle cells, reducing intracellular calcium, promoting vasodilation, and decreasing peripheral vascular resistance. It has a long half-life (35–50 hours) providing smooth 24-hour blood pressure control.
Key Benefits
- Dual-mechanism blood pressure control targeting two different pathways
- Amlodipine's long half-life provides smooth, around-the-clock blood pressure management
- Telmisartan may offer additional kidney and metabolic protective benefits
- Convenient once-daily combination reduces the number of tablets to take
Did You Know?
Telmisartan has one of the longest half-lives among all ARBs (about 24 hours), which means a single daily dose can maintain stable blood pressure control throughout the entire day and night — an important advantage for patients who may forget occasional doses.
When & How to Take
Telvex-AM is typically taken once daily, at the same time each day, with or without food, as prescribed by your doctor. Do not stop or adjust the dose without consulting your doctor, even if you feel well — hypertension often has no symptoms and needs consistent treatment.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Common side effects may include ankle or leg swelling (from Amlodipine), dizziness, headache, or flushing. Telmisartan may occasionally cause dizziness on standing (especially at the start of treatment). Tell your doctor if any side effect is severe or persistent.
Precautions & Safety
- Do not use during pregnancy — Telmisartan (ARB) is contraindicated in pregnancy as it can harm the unborn baby
- Monitor blood pressure and kidney function regularly as advised by your doctor
- Avoid potassium supplements or salt substitutes containing potassium without medical advice
- Rise slowly from sitting or lying to avoid dizziness from a sudden blood pressure drop
- Inform your doctor of all other medicines you take, especially diuretics or other antihypertensives
Myths vs Facts
Once your blood pressure comes down to normal, you can stop taking the tablet.
Blood pressure-lowering medicines control but do not cure hypertension. Stopping them usually causes blood pressure to rise again. Always consult your doctor before making any changes to your antihypertensive regimen.
High blood pressure only needs treatment when you have symptoms like headaches.
Hypertension is often called the 'silent killer' because it typically causes no symptoms until serious complications like stroke or heart attack occur. Regular treatment is essential regardless of how you feel.
