Cefzia-100 Dry Suspension
Cefixime 100 mg/5ml
| Composition | Cefixime 100 mg/5ml |
|---|---|
| Packing | 12gm/30 ml with Water |
| MRP | ₹ 72 |
| Dosage Form | Dry Syrups |
About Cefzia-100 Dry Suspension
Cefzia-100 Dry Suspension contains Cefixime 100 mg/5 ml, a third-generation cephalosporin antibiotic in a reconstituted dry suspension form, widely used for treating bacterial infections in children and adults who require a liquid formulation.
Cefixime is valued for its broad-spectrum activity against common gram-positive and gram-negative bacteria, excellent oral bioavailability, and once- or twice-daily dosing convenience. Biozia's Cefzia-100 Dry Suspension provides a reliable, easy-to-administer antibiotic for infections of the ear, throat, chest, and urinary tract.
Uses of Cefzia-100 Dry Suspension
This medicine is commonly used for:
- Ear infections (otitis media) in children
- Throat and tonsil infections (tonsillitis and pharyngitis) caused by susceptible bacteria
- Urinary tract infections including uncomplicated urinary tract infections
- Chest and respiratory tract infections such as acute bronchitis and community-acquired pneumonia
- Typhoid fever caused by susceptible Salmonella typhi
Indications
Cefixime is indicated for the treatment of infections caused by susceptible organisms including: otitis media, pharyngitis and tonsillitis (due to Streptococcus pyogenes), acute exacerbations of chronic bronchitis, community-acquired pneumonia (mild to moderate), uncomplicated urinary tract infections (Escherichia coli, Proteus mirabilis), uncomplicated gonorrhoea (cervical/urethral), and enteric fever (typhoid). It demonstrates stability against many beta-lactamases produced by gram-negative organisms.
How Cefzia-100 Dry Suspension Works
Cefixime is an antibiotic that works by attacking the protective wall surrounding bacterial cells. It blocks the bacteria from building this wall properly, causing the bacterial cell to burst and die. Because human cells do not have this type of cell wall, Cefixime can target bacteria without harming the body's own cells, making it an effective and safe antibiotic.
Mechanism of Action
Cefixime is an orally active third-generation cephalosporin that exerts bactericidal activity by binding to penicillin-binding proteins (PBPs), particularly PBP-3 and PBP-1, thereby inhibiting transpeptidation in bacterial cell wall (peptidoglycan) synthesis. This disrupts cross-linking of peptidoglycan chains, leading to osmotic instability and lysis of susceptible bacterial cells. Cefixime is resistant to many plasmid-mediated beta-lactamases produced by gram-negative organisms and demonstrates good activity against Enterobacteriaceae, Haemophilus influenzae, and Streptococcus species. It has limited activity against Staphylococcus aureus and Pseudomonas aeruginosa.
Key Benefits
- Third-generation cephalosporin with broad-spectrum coverage including common paediatric pathogens
- Once- or twice-daily dosing improves adherence and convenience
- Dry suspension form reconstitutes easily for accurate paediatric dosing
- Stable against many common beta-lactamase-producing bacteria, enhancing efficacy
Did You Know?
Cefixime was the first oral third-generation cephalosporin to be approved for clinical use and was introduced in the 1980s. Its oral bioavailability of approximately 40–50% is notably good for a cephalosporin, making it an effective option when intravenous antibiotics are not necessary or practical.
When & How to Take
Cefzia-100 Dry Suspension should be reconstituted with water as directed by the pharmacist or label before the first use. Shake well before each dose. It can be taken with or without food, as prescribed by your doctor. Complete the full prescribed course even if your child feels better.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Common side effects may include diarrhoea, stomach pain, nausea, or mild skin rash. Diarrhoea is one of the more frequently reported effects with Cefixime. These effects are generally mild and resolve after completing the course. Tell your doctor if any side effect is severe or persistent, or if a rash develops.
Precautions & Safety
- Inform your doctor of any allergy to penicillin or other cephalosporins before starting Cefixime, as cross-sensitivity may occur
- Always complete the full prescribed antibiotic course to prevent antibiotic resistance and relapse
- The reconstituted suspension should be stored in the refrigerator and used within the period specified on the label (typically 7–14 days)
- Inform your doctor if your child has kidney disease, as dose adjustment may be required
- Do not use for viral infections such as common cold or flu — antibiotics are ineffective against viruses
Myths vs Facts
A dry suspension antibiotic is less potent than a tablet or capsule.
The antibiotic content and therapeutic effect are equivalent. Dry suspensions are simply a preservation technique for keeping the antibiotic stable before reconstitution — once mixed with water, they deliver the same dose of Cefixime as a tablet or capsule.
Antibiotics can be stopped as soon as the child's fever goes down.
The infection may not be fully cleared when symptoms subside. Stopping antibiotics early can allow remaining bacteria to survive and cause a relapse, and may contribute to antibiotic resistance. Always complete the full prescribed course.
