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Topical NSAID Analgesic & Counter-Irritant Gel

Dicrex-Gel

Diclofenac Diethylamine 1.16% Eq. to Diclofenac Sodium 1% + Methyl Salicylate 10% + Oleum Lini 3% + Menthol 5% + Benzyl Alcohol 1% w/v

Composition Diclofenac Diethylamine 1.16% Eq. to Diclofenac Sodium 1% + Methyl Salicylate 10% + Oleum Lini 3% + Menthol 5% + Benzyl Alcohol 1% w/v
Packing 30 gm
MRP ₹ 70.13
Dosage Form Topical

About Dicrex-Gel

Dicrex-Gel is a topical analgesic and anti-inflammatory gel combining Diclofenac Diethylamine 1.16% (equivalent to Diclofenac Sodium 1%), Methyl Salicylate 10%, Oleum Lini (Linseed Oil) 3%, Menthol 5%, and Benzyl Alcohol 1%. This multi-ingredient formula delivers targeted pain relief directly to the site of discomfort, combining the proven anti-inflammatory action of diclofenac with the soothing counter-irritant effects of methyl salicylate and menthol.

Widely used for joint pain, muscle aches, sports injuries, and soft tissue inflammation, Dicrex-Gel is applied directly to the skin for localised relief without the systemic side effects associated with oral NSAIDs. The gel base ensures quick absorption and a non-greasy finish.

Uses of Dicrex-Gel

This medicine is commonly used for:

  • Relief from joint pain and arthritis-related inflammation
  • Muscle soreness, cramps, and sports injuries
  • Backache, neck pain, and shoulder pain
  • Soft tissue injuries including strains and sprains
  • Tendonitis and minor sports-related inflammation

Indications

Diclofenac Diethylamine topical gel is indicated for the local symptomatic relief of pain and inflammation in localised forms of soft tissue rheumatism, acute musculoskeletal injuries (sprains, strains, contusions), arthralgia (joint pain), low back pain, and periarticular conditions such as tendinitis and bursitis. Methyl salicylate and menthol act as counter-irritants providing additional symptomatic pain relief through cutaneous receptor modulation.

How Dicrex-Gel Works

When Dicrex-Gel is massaged into the skin, the diclofenac is absorbed locally into the underlying tissues, where it reduces the production of prostaglandins — chemicals the body makes in response to injury or inflammation that cause pain and swelling. Methyl salicylate and menthol create a warming and cooling sensation that further helps to soothe pain and discomfort at the surface level.

Mechanism of Action

Diclofenac is a non-selective COX-1 and COX-2 inhibitor that suppresses arachidonic acid conversion to prostaglandins and thromboxanes by blocking cyclooxygenase enzymes, thereby reducing local tissue inflammation and pain. As the diethylamine salt, it exhibits superior transdermal penetration compared with sodium salt formulations, achieving therapeutically relevant sub-cutaneous and synovial concentrations while minimising systemic absorption. Methyl salicylate (a salicylate ester) provides additional COX inhibition and counter-irritant analgesia through activation of TRPV1 thermal receptors. Menthol activates TRPM8 cold receptors, producing cooling analgesia and modulating pain signal transmission. Benzyl alcohol contributes mild local anaesthetic and antimicrobial properties.

Key Benefits

  • Targeted topical delivery reduces pain and inflammation at the site of injury with minimal systemic exposure
  • Multi-ingredient formula with NSAID, counter-irritant, and cooling mechanisms for comprehensive pain relief
  • Non-greasy gel base ensures quick absorption and comfortable application
  • Useful for a wide range of musculoskeletal pain conditions

Did You Know?

Diclofenac as a topical gel can reach therapeutically relevant concentrations in the synovial fluid of joints below the application site — without achieving significant levels in the bloodstream. This makes it a uniquely targeted option for joint pain with a much lower risk of stomach and cardiovascular side effects compared with oral diclofenac.

When & How to Take

Dicrex-Gel is for external use only. Apply a small amount to the affected area and massage gently until absorbed. Use as directed by your doctor, typically 3–4 times daily. Wash hands thoroughly after application. Avoid applying over large areas of skin or for prolonged periods beyond what is prescribed.

Always follow the dosage and schedule advised by your doctor — this is general guidance only.

Possible Side Effects

Local skin reactions such as redness, itching, burning, or mild rash may occur at the application site in some users. Rarely, an allergic skin reaction may develop. Systemic NSAID effects are uncommon with topical use but possible with extensive or prolonged application. Tell your doctor if any side effect is severe or persistent.

Precautions & Safety

  • For external use only — do not apply near the eyes, mouth, or on broken, infected, or inflamed skin
  • Avoid prolonged use over large surface areas without medical advice to limit any systemic absorption
  • Individuals with aspirin or NSAID hypersensitivity should consult a doctor before use
  • Do not use tight dressings or bandages over the area where gel has been applied
  • Consult your doctor before use if you are pregnant, breastfeeding, or have kidney, liver, or cardiovascular disease
  • Keep out of reach of children

Myths vs Facts

Myth

Applying more gel to a painful area will speed up recovery.

Fact

Using more than the recommended amount of topical diclofenac does not increase effectiveness and may increase the risk of skin irritation or systemic absorption. Always use the amount prescribed by your doctor.

Myth

Topical gels are just for surface pain and do not reach deeper joints.

Fact

Diclofenac gel has been shown in clinical studies to penetrate through the skin and reach sub-cutaneous tissue and synovial fluid in joints, providing genuine anti-inflammatory benefit at depth — not just a surface sensation.

Frequently Asked Questions

Dicrex-Gel is a topical pain relief gel used for joint pain, muscle soreness, sports injuries, backache, sprains, and tendonitis. It contains diclofenac for anti-inflammatory action, methyl salicylate and menthol for counter-irritant relief.
Prolonged or extensive use should only be under a doctor's guidance. Topical diclofenac is generally intended for short-term pain management. If joint pain persists, consult a doctor for a comprehensive treatment plan.
Topical diclofenac gels have significantly less systemic absorption than oral NSAIDs, making them a safer option for individuals with stomach concerns. However, individuals with serious stomach conditions should consult their doctor before use.
Do not wrap tight bandages over the area after applying the gel, as this can increase absorption. You may cover loosely with light clothing after the gel has absorbed.
Medical disclaimer: This information is for general awareness and education only and is not a substitute for professional medical advice. Dicrex-Gel is a pharmaceutical product to be used only as prescribed by a registered medical practitioner. Always read the package insert and consult your doctor or pharmacist before use. Biozia Lifesciences markets this product to licensed pharmacy and healthcare businesses.

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