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NSAID + Analgesic & Antipyretic Combination (Paediatric)

Mefzia-P Kid Suspension

Mefenamic Acid 50 mg + Paracetamol 125 mg

Composition Mefenamic Acid 50 mg + Paracetamol 125 mg
Packing 60ML
MRP ₹ 45
Dosage Form Syrups & Suspensions

About Mefzia-P Kid Suspension

Mefzia-P Kid Suspension is a paediatric analgesic and antipyretic suspension containing Mefenamic Acid 50 mg and Paracetamol 125 mg per 5 ml dose. Designed for young children, it combines the anti-inflammatory and analgesic action of Mefenamic Acid with the trusted fever-reducing and pain-relieving action of Paracetamol in a lower-strength, child-appropriate formulation.

Mefzia-P Kid Suspension is commonly prescribed by paediatricians for children experiencing pain and fever associated with teething, ear infections, throat infections, and other common childhood conditions where both NSAID and paracetamol activity is needed for better symptom control.

Uses of Mefzia-P Kid Suspension

This medicine is commonly used for:

  • Relieving mild to moderate pain in young children
  • Reducing fever in children with infections
  • Managing pain from teething, ear infections, and sore throat
  • Relieving body aches and discomfort during febrile illness
  • Providing dual analgesic and anti-inflammatory relief in children

Indications

Mefzia-P Kid Suspension is indicated for the paediatric symptomatic management of mild to moderate pain and pyrexia in conditions such as teething pain, otitis media, pharyngitis, tonsillitis, post-immunisation fever, and musculoskeletal pain. Mefenamic Acid provides NSAID-mediated analgesic and anti-inflammatory activity via COX inhibition; Paracetamol provides complementary centrally mediated analgesic and antipyretic activity with gastric safety, enabling a lower dose of Mefenamic Acid while maintaining therapeutic efficacy.

How Mefzia-P Kid Suspension Works

Mefzia-P Kid Suspension works through the combined actions of its two ingredients: Mefenamic Acid reduces inflammation and pain at the site of injury or infection by blocking the enzymes that produce pain-causing chemicals, while Paracetamol acts in the brain to raise the pain threshold and reduce fever. Together, these two mechanisms provide more comprehensive pain and fever relief than either medicine alone, especially useful for children dealing with painful infections.

Mechanism of Action

Mefenamic Acid is a non-selective COX-1 and COX-2 inhibitor of the fenamate NSAID class. It inhibits prostaglandin synthesis peripherally and centrally, reducing inflammatory mediator production at the site of tissue injury, thereby providing analgesic, anti-inflammatory, and mild antipyretic effects. Paracetamol exerts antipyretic activity through inhibition of central hypothalamic prostaglandin synthesis and analgesia via central COX-3 isoenzyme inhibition and modulation of descending serotonergic nociceptive pathways. The combination achieves synergistic analgesic and antipyretic efficacy through complementary peripheral (Mefenamic Acid) and central (Paracetamol) mechanisms of action.

Key Benefits

  • Dual mechanism provides better pain and fever control than single agents in children
  • Paediatric-appropriate lower doses of both ingredients for child safety
  • Mefenamic Acid adds anti-inflammatory action beyond simple paracetamol
  • Liquid suspension format for easy administration to young children

Did You Know?

Mefenamic Acid belongs to the fenamate class of NSAIDs, which are unusual among NSAIDs in that they not only inhibit prostaglandin synthesis but also block prostaglandin receptors directly — giving them a double layer of anti-inflammatory and analgesic activity that makes them particularly effective for acute pain conditions.

When & How to Take

Mefzia-P Kid Suspension should be given only as directed by your child's paediatrician. It is generally given with or after food to reduce the chance of stomach irritation from Mefenamic Acid. Shake the bottle well before use. Do not exceed the prescribed dose.

Always follow the dosage and schedule advised by your doctor — this is general guidance only.

Possible Side Effects

Mild nausea, stomach discomfort, or loose stools may occasionally occur due to Mefenamic Acid. Paracetamol is generally well tolerated. Long-term use of NSAIDs in children should be avoided without medical supervision. Tell your doctor if any side effect is severe or persistent.

Precautions & Safety

  • Always give with or after food to reduce stomach irritation
  • Do not give alongside other NSAID medicines or additional paracetamol products
  • Inform the doctor if the child has kidney, liver, or stomach problems
  • Avoid in children with known aspirin or NSAID sensitivity
  • Shake the bottle well before each dose

Myths vs Facts

Myth

Giving two different pain medicines to a child is always dangerous.

Fact

When prescribed by a doctor in correct doses, combining Mefenamic Acid and Paracetamol is safe and often more effective than either alone. The combination in Mefzia-P Kid is specifically formulated to work synergistically at child-appropriate doses.

Myth

Paediatric suspensions with NSAIDs should only be used for very serious conditions.

Fact

NSAIDs like Mefenamic Acid are commonly and safely used in children for everyday painful conditions like teething, ear pain, and throat infections — as long as the dose and duration are as prescribed by the paediatrician.

Frequently Asked Questions

Mefzia-P Kid Suspension is used to relieve mild to moderate pain and fever in young children — for conditions such as ear infections, teething, sore throat, and post-vaccination fever.
Yes, it is generally recommended to give it with or after a light meal to reduce stomach discomfort from the Mefenamic Acid component.
No — Mefzia-P Kid already contains Paracetamol. Giving additional paracetamol risks overdose. Always consult your paediatrician before combining any medicines.
Medical disclaimer: This information is for general awareness and education only and is not a substitute for professional medical advice. Mefzia-P Kid Suspension is a pharmaceutical product to be used only as prescribed by a registered medical practitioner. Always read the package insert and consult your doctor or pharmacist before use. Biozia Lifesciences markets this product to licensed pharmacy and healthcare businesses.

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