Zianac-P Tablet
Aceclofenac 100 mg + Paracetamol 325 mg
| Composition | Aceclofenac 100 mg + Paracetamol 325 mg |
|---|---|
| Packing | 10x10 Blister & Alu Alu |
| MRP | 700/850 |
| Dosage Form | Tablets |
About Zianac-P Tablet
Zianac-P Tablet is a well-established combination tablet containing Aceclofenac 100 mg and Paracetamol 325 mg — two complementary pain relievers that together provide effective relief from mild to moderate pain and inflammation.
Widely used across orthopaedic, dental, and general practice settings, Zianac-P offers dual-action analgesia in a convenient single tablet.
Uses of Zianac-P Tablet
This medicine is commonly used for:
- Joint pain and arthritis-related discomfort
- Dental pain and toothache
- Post-surgical and post-traumatic pain
- Menstrual (period) pain
- Headache, body ache, and fever
Indications
Aceclofenac + Paracetamol is indicated for the symptomatic relief of mild to moderate pain in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-operative pain, dysmenorrhoea, and pyrexia. This combination leverages dual analgesic pathways for enhanced pain control with a balanced tolerability profile.
How Zianac-P Tablet Works
Aceclofenac reduces pain and swelling by blocking inflammatory chemicals called prostaglandins. Paracetamol adds to this effect by acting on the brain's pain centres to raise the pain threshold. Together, they provide more complete pain relief than either ingredient alone.
Mechanism of Action
Aceclofenac preferentially inhibits cyclooxygenase-2 (COX-2), suppressing prostaglandin E2 synthesis at sites of inflammation and thereby reducing peripheral sensitisation. Paracetamol inhibits central COX isoforms, modulates the endocannabinoid system, and activates descending serotonergic inhibitory pathways — producing analgesia and antipyresis without significant peripheral anti-inflammatory activity.
Key Benefits
- Dual-mechanism pain relief for more comprehensive analgesia
- Anti-inflammatory action helps reduce swelling alongside pain
- Good tolerability with a lower gastric side-effect burden compared to older NSAIDs
- Useful across a wide range of painful conditions
Did You Know?
Clinical studies suggest that combining Aceclofenac with Paracetamol can achieve pain relief comparable to higher doses of either drug alone — meaning you benefit from synergy while each ingredient can be used at a moderate dose.
When & How to Take
Zianac-P Tablet should be taken with or after food to minimise stomach upset. Use it for the duration and frequency prescribed by your doctor, and do not self-medicate for extended periods.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Common side effects may include nausea, indigestion, or mild stomach discomfort. Occasional dizziness or headache may occur. These effects are generally mild. Tell your doctor if any side effect is severe or persistent.
Precautions & Safety
- Always take with food to protect the stomach lining
- Avoid alcohol while taking this tablet
- Inform your doctor if you have a history of peptic ulcer, liver, or kidney disease
- Avoid combining with other NSAIDs or paracetamol-containing medicines
- Use with caution during pregnancy and breastfeeding — consult your doctor
Myths vs Facts
NSAIDs are the same as steroids.
NSAIDs like Aceclofenac are non-steroidal — they relieve pain and inflammation through a completely different mechanism than steroids and do not carry the same risks associated with long-term steroid use.
Paracetamol is completely harmless at any amount.
Paracetamol is safe at recommended doses, but taking more than prescribed can cause serious liver damage. Always stick to the dose your doctor recommends.
