Scazia Lotion
Permethrin 5% w/w Lotion
| Composition | Permethrin 5% w/w Lotion |
|---|---|
| Packing | 50 ml |
| MRP | ₹ 55 |
| Dosage Form | Dry Syrups |
About Scazia Lotion
Scazia Lotion contains Permethrin 5% w/w, a highly effective synthetic pyrethroid antiparasitic agent used for the topical treatment of scabies — a highly contagious skin infestation caused by the mite Sarcoptes scabiei. Scazia Lotion is applied to the skin and left on to kill the mites and their eggs, providing thorough relief from the intense itching and skin discomfort scabies causes.
Permethrin 5% is recommended by dermatologists and recognised health authorities as a first-line treatment for scabies. Scazia Lotion is easy to apply, works on a single application in most cases, and is suitable for adults and children above the recommended age as advised by a doctor.
Uses of Scazia Lotion
This medicine is commonly used for:
- Treatment of scabies (mite infestation causing intense itching and skin rash)
- Treatment of head lice and pubic lice (pediculosis)
- Used as a preventive treatment for close contacts of a scabies patient
- Itching and skin rash caused by parasitic mite infestation
Indications
Permethrin 5% topical lotion is indicated for the topical treatment of scabies due to Sarcoptes scabiei in adults and children aged 2 months and above. It is also used in the management of pediculosis capitis (head lice) and pediculosis pubis (pubic lice). Application to all household and close contacts is recommended to prevent reinfestation.
How Scazia Lotion Works
Permethrin works by interfering with the nervous system of parasitic mites and lice. It disrupts the normal electrical signals in their nerve cells, causing paralysis and death of the parasites. A single overnight application to the entire body is usually sufficient to eliminate the infestation.
Mechanism of Action
Permethrin is a synthetic type I pyrethroid that exerts its antiparasitic effect by binding to voltage-gated sodium channels in the neuronal membranes of arthropods, prolonging sodium channel opening. This results in repetitive neuronal discharges, paralysis, and death of Sarcoptes scabiei mites, their eggs, and louse species. Mammalian sodium channels are far less sensitive to permethrin and the compound undergoes rapid hydrolytic detoxification in human tissues, accounting for its selective toxicity to parasites.
Key Benefits
- First-line treatment for scabies with a single overnight application in most cases
- Ovicidal (kills eggs) as well as lethal to adult mites, reducing the chance of reinfestation
- Minimal systemic absorption due to rapid cutaneous metabolism, making it generally safe
- Also effective against head lice, broadening its antiparasitic utility
Did You Know?
Even after successful scabies treatment, itching can continue for up to 4 weeks. This is because the body's immune system continues to react to the dead mites and their waste products in the skin — it does not necessarily mean the treatment has failed.
When & How to Take
Scazia Lotion is for external use only. Apply as directed by your doctor — typically a thorough application to the entire body from neck to toes (including skin folds and under the nails) and left on for the duration recommended before washing off. Follow your doctor's instructions on whether a second application is needed and when to treat close contacts.
Always follow the dosage and schedule advised by your doctor — this is general guidance only.
Possible Side Effects
Some temporary stinging, burning, or itching at the application site may occur, particularly in areas of broken or inflamed skin. Mild redness or a rash may be noticed. These effects are usually short-lived. Tell your doctor if any side effect is severe or persistent, or if you develop signs of an allergic reaction.
Precautions & Safety
- Keep the lotion away from the eyes, nose, and mouth; rinse thoroughly with water if contact occurs
- Do not use on broken or severely inflamed skin without medical advice
- Wash all clothing, bedding, and towels used in the 48 hours before treatment to prevent reinfestation
- Treat all household members and close physical contacts simultaneously, as recommended by your doctor
- Consult a doctor before use in infants under 2 months, during pregnancy, or while breastfeeding
Myths vs Facts
Scabies is a sign of poor hygiene.
Scabies is caused by a microscopic mite and spreads through prolonged skin-to-skin contact — it can affect anyone, regardless of their cleanliness habits. The mite does not discriminate based on hygiene.
If I still itch after applying the lotion, it means the treatment did not work.
Post-treatment itching is very common and can last several weeks even after the mites are fully eliminated. This is an immune reaction, not a sign of treatment failure. Your doctor can advise on symptom relief during this period.
